This is the basic science research unit of the Department of Radiation Oncology at The Division of Molecular Radiation Sciences (MRS) at The Johns Hopkins University School of Medicine focuses on understanding the DNA damage response and repair pathways involved in human cancer and bridges basic science and translational research.
The research teams investigate how genetic errors lead to cancer, and how these errors are tackled by repair machineries at the molecular level. This knowledge is used to understand how cancers arise and to discover and develop new cancer therapies that exploit the sensitivities of the cancers to excessive damage. In radiation therapy, these principles are put into effective use – therapeutic targeting of the cancers while leaving the healthy tissues intact.
Our faculty members and their teams are engaged also in clinical and medical physics research in radiation oncology and have substantive collaborations and interactions with the Sidney Kimmel Comprehensive Cancer Center programs. The activities at the Molecular Radiation Sciences division have generated extensive research synergism and continue to provide transdisciplinary advances in basic sciences, pre-clinical and early clinical investigation.
We train and mentor undergraduate and graduate students and fellows from diverse backgrounds and value and promote a climate of respect and inclusion.
MRS is located in the David H. Koch Cancer Research Building 2 at the East Baltimore Campus of the Johns Hopkins Medical Institutions, in close proximity to a multitude of state-of-the art research facilities and core services.